Equipment Reference
Double Wood Supplements
Double Wood Apigenin 50mg
120 capsules — the Huberman sleep-stack flavonoid from chamomile
Double Wood Apigenin is 50mg per capsule — the dose Andrew Huberman cites in his evening stack with magnesium and L-theanine. Chamomile’s primary flavonoid, third-party tested, 120-count (two months at one capsule). Human sleep RCTs on isolated apigenin are thin; this is a low-risk add-on after magnesium is already working.
Health Disclaimer
This content is for general informational and educational purposes only. It is not medical advice, diagnosis, or treatment. Consult a qualified healthcare provider before starting any supplement, peptide, or health protocol. Read our full health disclaimer.
Typical price: $18 – $26 USD / 120 capsules
How It Works
Apigenin is a flavone in chamomile, parsley, and celery. Chamomile tea trials support mild sleep/anxiety effects; isolated 50mg capsule data is mostly mechanistic and anecdotal. Also discussed as a senolytic in lab work — sleep is the practical use here.
GABA-A Modulation
Apigenin binds GABA-A receptors with mild calming effects — closer to chamomile tea than a hypnotic.
50mg Capsule
Matches the commonly cited Huberman dose. One capsule 30–60 minutes before bed.
Stack Last
Add after magnesium (and optional glycine/theanine). Do not start four new sleep pills the same week.
What You'll Experience
First Week
Nights 1–7Subtle easier wind-down for some; others notice nothing beyond the ritual.
Keep or Drop
Week 3–4If sleep onset did not change, keep magnesium and drop apigenin. No withdrawal.
Benefits
Huberman-Dose Convenience
Anecdotal50mg without brewing tea or guessing powder scoops.
Low Side-Effect Profile
Emerging ResearchGenerally well tolerated at 50mg in healthy adults.
Risks & Considerations
Sedating Meds
medium riskTheoretical additive effect with benzos, Z-drugs, or alcohol — do not combine casually.
Pregnancy
medium riskHigh-dose isolated flavonoids are not well studied in pregnancy — skip.
Community Reviews
Synthesized consensus from Reddit, forums, and expert sources.
Believers report smoother sleep onset; skeptics say magnesium did all the work. Consensus: cheapest stack piece after magnesium.
- ·50mg is the number
- ·Add last
- ·Not a substitute for apnea care
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