Protocols
Biohacking Protocols
Quick-reference protocols with links to full guides. Learn the science first, then follow the protocol.
Buying Guides
Head-to-head comparisons and best-of roundups — start here when you're ready to purchase.
Oura Ring vs WHOOP (2026): Ring vs Band, Cost & Which to Buy
Oura and WHOOP are the two wearables biohackers debate most. Oura excels at passive sleep staging and HRV detail in an unobtrusive ring. WHOOP excels at training load management with its strain/recovery loop. This guide compares accuracy, pricing, use cases, and who should buy which. Considering Garmin too? See Garmin Fenix vs Oura vs WHOOP.
Garmin Fenix vs Oura vs WHOOP: Training Watch, Sleep Ring, or Strain Band?
Garmin Fenix, Oura Ring, and WHOOP represent three fundamentally different philosophies of wearable tracking. Fenix is a GPS multisport training computer built for structured athletes who need mapping, workout metrics, and multi-week battery life. Oura is a passive sleep and recovery ring built for people who want health insight without any active engagement. WHOOP is a screenless strain-and-recovery band built around a daily push-or-rest decision loop. This guide compares all three across sleep tracking, training features, battery life, pricing, and helps you decide whether you need one, two, or all three. Narrowed to ring vs band only? See Oura vs WHOOP.
Eight Sleep vs BedJet vs Sleepme Dock Pro (Chilipad): Which Sleep Cooling System Wins?
Sleep temperature regulation is one of the highest-leverage biohacks with genuine evidence behind it, and three systems dominate the category: Eight Sleep Pod, BedJet 3, and Sleepme's Dock Pro (the modern successor to Chilipad, now owned and re-engineered by the same Sleepme team). Eight Sleep uses hydronic water cooling built into a mattress cover with deep sleep-stage automation. BedJet uses forced air instead of water, with no wet components at all. Sleepme's Dock Pro is the direct descendant of the original Chilipad, focused purely on precise temperature control without the smart-home layer. This guide compares the technology, noise, subscriptions, price, and who should buy which. Want the science and budget tiers first? Read Sleep Cooling.
Best Red Light Therapy Panel for Home Use: A Biohacker's Buying Guide
Red light therapy (photobiomodulation) panels range from $150 travel-size units to $2,000+ full-body clinical panels, and price alone tells you almost nothing about effectiveness. What actually matters is irradiance at a realistic treatment distance, wavelength accuracy at 630–670nm (red) and 810–850nm (near-infrared), and whether the company publishes third-party testing. This guide compares Joovv's Elite panel, Hooga's budget-friendly HG panel, Mito Red's Mitopro line, and CurrentBody's LED mask for facial use, then breaks down how to choose based on your goals and budget. New to the science? Start with our Red Light Therapy complete guide.
Best Air Purifier for Biohackers: HEPA, VOC, and CADR Compared
Indoor air quality is an underrated biohacking lever, chronic exposure to fine particulates (PM2.5), VOCs, and allergens is linked to worse sleep, higher inflammatory markers, and reduced cognitive performance. But the air purifier market is full of inflated CADR claims and marketing around 'medical grade' filtration that doesn't always translate to real-world benefit. This guide compares IQAir's HealthPro Plus, AirDoctor's 5500, Blueair's Classic line, and Coway's Airmega, and explains which specs actually matter for a bedroom-focused biohacking setup. Broader home toxins context: Environmental Health. Water side: Water Filtration.
Best Water Filter for Biohackers: Berkey vs AquaTru vs Waterdrop Compared
Tap water carries PFAS, fluoride, lead, and microplastics — biohackers filter drinking water for the same reason they filter air. This guide compares Berkey gravity filters, AquaTru countertop reverse osmosis, and Waterdrop under-sink tankless RO by contaminant removal, installation, and cost. For the science on filter types and regional water quality, see our Water Filtration guide.
Plunge vs Ice Barrel: Which Cold Plunge Should You Buy?
Home cold plunges split into two camps: chiller-equipped tubs like the Plunge All-In ($5,000) that hold 39°F without ice, and manual barrels like the Ice Barrel 300 ($1,200) where you add ice each session. Both deliver Huberman's 11 min/week protocol — the difference is convenience, running costs, and whether you'll actually use it daily. For the full science and free-to-premium path, start with our Cold Exposure guide.
Protocol Stacks
Infrared Sauna Protocol
Strong EvidenceHuberman and Rhonda Patrick's most-cited longevity intervention. 140°F+ for 20+ minutes.
Cold Exposure Protocol
Moderate EvidenceHuberman's minimum effective dose in uncomfortably cold water.
Sleep Optimization Protocol
Strong EvidenceTemperature, light, and tracking. The foundation of every biohack.
Red Light Therapy Protocol
Moderate EvidenceMorning photobiomodulation at 660nm + 850nm.
HRV Recovery Protocol
Moderate EvidenceTrain based on recovery, not motivation.
CGM Metabolic Protocol
Strong EvidencePersonalized nutrition through real-time glucose data.
NAD+ Longevity Protocol
Emerging EvidenceNR or NMN with TMG methyl donor support.
Creatine Protocol
Strong Evidence5g monohydrate for muscle, brain, and healthy aging.
Magnesium Sleep Protocol
Moderate Evidence200–400mg glycinate 30–60 min before bed.
Blueprint Core Stack
Moderate EvidenceBryan Johnson's evidence-based essentials, not the full 100-pill stack.
Zone 2 Cardio Protocol
Strong EvidencePeter Attia's mitochondrial foundation: conversational pace cardio.
Breathwork Protocol
Moderate EvidenceBox breathing, Wim Hof, and physiological sigh for nervous system control.
Foundation Supplement Stack
Strong EvidenceCreatine, magnesium, vitamin D+K2, omega-3. The tier-1 stack.
Contrast Therapy Protocol
Moderate EvidenceIntermittent Fasting Protocol
Moderate EvidenceDave Asprey's foundational metabolic biohack: 16:8 with fat-fueled mornings.
Bulletproof Coffee Protocol
Moderate EvidenceCoffee + C8 MCT + grass-fed butter for ketone-fueled focus.
Vagus Nerve Toning Protocol
Moderate EvidenceCold face immersion, slow breathing, and humming for nervous system resilience.
Neurofeedback Protocol
Moderate EvidenceEEG brain training for focus, calm, and meditation depth.
Huberman Sleep Stack
Emerging EvidenceApigenin 50mg + magnesium 200–400mg + theanine 100–200mg for sleep onset support.
Lion's Mane Nootropic Protocol
Moderate Evidence500–1000mg dual-extract lion's mane for cognitive support.
Ashwagandha Stress Protocol
Moderate Evidence600mg KSM-66 for cortisol reduction and stress resilience.
Blood Panel Baseline Protocol
Strong EvidenceComprehensive biomarker testing with ApoB, insulin, and thyroid.
BPC-157 Recovery Protocol
Emerging Evidence250–500mcg subcutaneous for tissue and gut healing.
TB-500 Recovery Protocol
Emerging Evidence2–2.5mg subcutaneous for tissue migration and joint recovery.
Glycine Sleep Protocol
Moderate Evidence3g glycine powder 30–60 min before bed for core temperature drop.
Circadian Rhythm Protocol
Strong EvidenceMorning sunlight within 60 min of waking, dim lights after sunset.
Grounding Protocol
Emerging EvidenceBarefoot outdoor contact or indoor grounding mat during sleep/work.
Urolithin A Longevity Protocol
Moderate Evidence500mg urolithin A for mitophagy and mitochondrial health.
Collagen Peptides Protocol
Moderate Evidence10–15g hydrolyzed collagen in morning coffee or smoothie.
Blue Light Blocking Protocol
Moderate EvidenceAmber lenses plus dimmed overhead lights for melatonin protection.
Epitalon Longevity Cycle
Emerging Evidence5–10mg subcutaneous for pineal and telomerase support.
L-Theanine Calm Protocol
Moderate Evidence100–400mg theanine for calm focus or evening wind-down.
D3 + K2 Protocol
Moderate Evidence2000–5000 IU D3 + 100–200mcg K2 with fat-containing meal.
Mouth Tape Nasal Breathing
Emerging EvidencePorous vertical tape strip for nasal breathing and snoring reduction.
Berberine Metabolic Protocol
Moderate Evidence500mg berberine per meal for glucose control and AMPK activation.
Rhodiola Morning Protocol
Moderate Evidence200–400mg standardized extract before breakfast for calm energy.
NAC Glutathione Protocol
Moderate Evidence600–1200mg NAC on empty stomach for antioxidant and liver support.
CoQ10 Mitochondrial Protocol
Moderate Evidence100–400mg ubiquinol with fatty meal, especially if on statins.
Tongkat Ali Testosterone Protocol
Moderate Evidence200–400mg standardized extract with baseline and follow-up bloodwork.
LMNT Electrolyte Protocol
Strong Evidence1000mg sodium packet during fasting, sauna, or heavy training.
Oura vs WHOOP Decision Guide
Strong EvidenceCompare sleep tracking, strain coaching, and subscription costs.
Zinc Immune Protocol
Moderate Evidence15–30mg zinc picolinate with food for immune and hormonal support.
Probiotic Gut Protocol
Moderate Evidence10–50B CFU of clinically studied strains with prebiotic fiber.
Cryotherapy Protocol
Moderate EvidenceWhole-body cryo or ice bath for recovery and norepinephrine boost.
Spermidine Autophagy Protocol
Emerging Evidence1–6mg spermidine from wheat germ extract for cellular cleanup.
Shilajit Vitality Protocol
Emerging Evidence250–500mg purified shilajit resin for energy and testosterone support.
Peptides Introduction Protocol
Emerging EvidenceUnderstand peptide classes, sourcing, and safety before starting.
HBOT Recovery Protocol
Moderate EvidenceHyperbaric oxygen at 1.5–2.0 ATA for tissue repair and recovery.
Omega-3 Protocol
Strong Evidence2–3g combined EPA+DHA for cardiovascular and brain health.
Vitamin D Protocol
Strong Evidence2000–5000 IU D3 with K2, test blood levels twice yearly.
Gut Microbiome Protocol
Moderate EvidenceDiverse fiber, fermented foods, and targeted testing.
Testosterone Optimization Protocol
Moderate EvidenceSleep, lifting, zinc, tongkat ali, and baseline blood panels.
Glutathione Support Protocol
Moderate EvidenceNAC, glycine, and sulfur-rich foods for master antioxidant production.
Environmental Health Protocol
Moderate EvidenceAir purification, water filtration, and toxin reduction at home.
Nootropics Starter Protocol
Emerging EvidenceBegin with lion's mane, L-theanine, and caffeine before advanced stacks.
AG1 Daily Greens Protocol
Moderate EvidenceOne scoop greens powder in water each morning for micronutrient coverage.
Sleep Cooling Protocol
Strong Evidence65–68°F bedroom, warm bath 90 min pre-bed, active cooling if needed.
Fisetin Senolytic Pulse
Emerging Evidence1000mg fisetin/day for 2 days to clear senescent cells.
Methylene Blue Micro-Dose
Emerging Evidence0.5–4mg pharma-grade methylene blue — never with SSRIs.
Home Water Filtration
Strong EvidenceTest tap water, install RO or gravity filter for PFAS and lead removal.
GHK-Cu Peptide Protocol
Moderate Evidence1–2mg subQ or topical 1–2% serum for skin and tissue repair.
Stem Cell Therapy Overview
Emerging EvidenceUnderstand stem cell types, clinics, and realistic outcome expectations.
Strength Training Protocol
Strong EvidenceFull-body compounds, progressive overload, protein and creatine for muscle longevity.
VO2 Max Protocol
Strong EvidenceConversational cardio plus a weekly 4×4 or hill-repeat stimulus.
Taurine Longevity Protocol
Emerging Evidence1–3g taurine from food or capsules — cheap add-on, not a life-extension proof.
Rapamycin Longevity Overview
Emerging EvidencemTOR science and ITP mouse data — prescription only, no DIY sourcing.
GLP-1 Metabolic Overview
Strong EvidenceSemaglutide/tirzepatide evidence plus muscle-preserving training and protein.
NSDR / Yoga Nidra Protocol
Moderate EvidenceGuided non-sleep deep rest for afternoon recovery without wrecking nighttime sleep.
Protein for Longevity
Strong Evidence1.2–1.6 g/kg/day with leucine-rich meals to preserve muscle during aging and GLP-1 therapy.
Metformin Longevity Protocol
Moderate EvidenceTAME trial context, berberine comparison, and exercise interaction cautions.
Microplastics Reduction
Emerging EvidenceFilter water, swap containers, and reduce plastic heat exposure to lower body burden.
Hydrogen Water Protocol
Emerging EvidenceMolecular hydrogen tablets or generators for oxidative stress and recovery.
PEMF Recovery Protocol
Moderate EvidencePulsed electromagnetic field therapy for pain, sleep, and tissue recovery.
Oral Microbiome Protocol
Moderate EvidenceNasal breathing, tongue scraping, and oral hygiene for sleep and systemic health.
Electrolyte & Sodium Protocol
Strong EvidenceSodium and potassium replacement for sweat, sauna, fasting, and low-carb adaptation.
Compression Recovery Protocol
Moderate EvidencePneumatic boot sessions after leg-heavy training or travel.
Daily Walking Protocol
Strong EvidenceNEAT steps plus post-meal walks for mortality and glucose benefits.
Caffeine Timing Protocol
Moderate EvidenceDelay morning caffeine, stack L-theanine, hard cutoff before bed.
Infrared Sauna Blanket Protocol
Moderate EvidenceApartment-friendly FIR heat sessions with hydration and contrast options.
Rucking Protocol
Moderate EvidenceWeighted walking at Zone 2 for bone, strength-endurance, and low-impact cardio.
ApoB Lipid Panel Protocol
Strong EvidenceApoB, Lp(a), and lifestyle levers for cardiovascular longevity.
Mitochondrial Stack Protocol
Moderate EvidenceCoQ10, NAD+ precursors, and urolithin A with exercise-first hierarchy.
Red Light Face Mask Protocol
Moderate EvidenceLED mask sessions for skin collagen and texture over 8–12 weeks.
Stress Wearable Protocol
Emerging EvidenceApollo or Sensate sessions plus HRV tracking with Oura.
Bone Density Protocol
Strong EvidenceDEXA screening, heavy lifting, D3/K2, and protein for structural longevity.
Indoor Air Quality Protocol
Strong EvidenceSized HEPA filtration for PM2.5 and smoke reduction where you sleep.
Countertop Water Filter Protocol
Moderate EvidenceRO or gravity filtration with scheduled filter replacements.
Glucose Spike Control Protocol
Strong EvidencePost-meal walks, food order, and optional berberine with CGM learning phases.
Muse Meditation Protocol
Moderate EvidenceEEG-guided meditation sessions to build consistent practice.
Gundry Gut Check Protocol
Emerging EvidenceLectin-aware eating, fermented foods, and microbiome repair per Gundry's Plant Paradox series.
Sinclair Longevity Protocol
Emerging EvidenceTime-restricted eating, exercise, cold exposure, and NAD+ support per Lifespan.
William Li Eat to Beat Protocol
Moderate Evidence5×5×5 add-foods plan: angiogenesis, regeneration, microbiome, DNA protection, immunity.