
Equipment Reference
NOW Foods
NOW Foods Inositol 500 mg
NOW Foods Inositol 500mg review — pure myo-inositol capsules for Andrew Huberman's 900mg sleep-maintenance stack and insulin-signaling support.
Myo-inositol capsules — sleep, insulin signaling, and Huberman-adjacent dosing
NOW’s 500 mg myo-inositol capsule is the cheap way to try the sleep-and-insulin compound Huberman and PCOS clinics talk about. Clinical PCOS protocols often use grams, not one capsule — this bottle is a starter, not a 4 g powder tub. Pair with magnesium and glycine if sleep is the actual goal.
Health Disclaimer
This content is for general informational and educational purposes only. It is not medical advice, diagnosis, or treatment. Consult a qualified healthcare provider before starting any supplement, peptide, or health protocol. Read our full health disclaimer.
Typical price: $8 – $16 USD / 100 veg capsules
How It Works
Inositol phosphates are second messengers for insulin and several receptors. PCOS literature is the strongest clinical use. Sleep evidence is thinner and mostly anecdotal plus small trials. This is not a replacement for metformin you already take.
Myo-Inositol
The abundant form. Involved in insulin signaling and some neurotransmitter pathways. Not a sedative like melatonin.
Dose Honesty
500 mg is convenient. Sleep anecdotes are often 1–2 g; PCOS trials are often 2–4 g myo with D-chiro. Read the guide before stacking bottles.
With Food or Night
Night dosing is the sleep-stack habit. Insulin-protocol users often split doses. Pick one goal.
What You'll Experience
Sleep trial
1–2 weeksSome people sleep easier; many feel nothing. Do not add it on top of four other new sleep pills.
Metabolic
MonthsPCOS and insulin outcomes need grams and a clinician, not one 500 mg capsule.
Benefits
Cheap Trial Bottle
Emerging ResearchSee if you notice sleep before you buy a 4 g powder.
Known Form
Moderate EvidenceMyo-inositol, not a mystery blend with ashwagandha hiding in the same capsule.
Risks & Considerations
GI Upset at Grams
medium riskHigher PCOS-style doses can cause nausea and diarrhea. Titrate.
Not a Fertility Drug You Self-Prescribe
medium riskPCOS and pregnancy plans belong with a clinician.
Community Reviews
Synthesized consensus from Reddit, forums, and expert sources.
Sleep reviewers are split. PCOS reviewers often say they needed more than 500 mg. The smart comments treat it as a trial bottle.
- ·500 mg
- ·Myo-inositol
- ·Night or split
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Read guideLast updated: 2026-09-22 · Informational only. Not medical advice. Health disclaimer.


